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Product introduction:

Entacapone is an anti Parkinson's disease drug, developed by Orion Pharma of Sweden. It is a highly selective and powerful catechol-O-methyltransferase (COMT) inhibitor, which rarely penetrates the blood cerebrospinal fluid barrier and mainly functions in the gut. 

市场价:

  • Product information
  • 产品描述
  • 参数配置


1、 Product introduction

Chinese Name

English Name 

Declaration Type

Department

Reportable Dosage Form

Declaration Progress 

Strength

CAS
恩他卡朋Entacapone 5+4Psychiatry Department Tablet 

Already accepted

12.5mg、25mg、37.5mg、50mg、75mg、100mg、 150mg、200mg130929-57-6

Indication】

      Parkinson's disease. 


Reportable Dosage Form &Strength

      Tablet  :12.5mg、25mg、37.5mg、50mg、75mg、100mg、 150mg、200mg


Mechanism of Action

     Catechol-O-methyltransferase (COMT) inhibitor. Inhibition of COMT reduced the metabolism of levodopa to 3-oxo-methyldopa (3-OMD), which increased the bioavailability of levodopa and the total amount of levodopa available in the brain. 

Development Progress】

     Already accepted


2、 Clinical Advantages 


       It reduces the metabolism of levodopa to 3-oxo-methyldopa (3-OMD) by inhibiting COMT enzyme, which increases the bioavailability of levodopa and the total amount of available levodopa in the brain 



3Domestic Declaration



Declaration Type

Reportable Dosage Form

Number of Declared Preparations

Number of Existing Preparation Enterprises 

5+4Tablet 

domestic

imported 




 Brinzolamide 布林佐胺 CAS号:138890-62-7

Guangzhou Tosun Pharmaceutical Ltd

FL 4-5,No.3, 2nd Kehui street, Science Park, Guangzhou High-tech Industrial Development Zone, Guangzhou, China. 510663

Tel: +86-20-66392521; Fax: +86-20-66392525

Entacapone is an anti Parkinson's disease drug, developed by Orion Pharma of Sweden. It is a highly selective and powerful catechol-O-methyltransferase (COMT) inhibitor, which rarely penetrates the blood cerebrospinal fluid barrier and mainly functions in the gut. 

An anti Parkinson's drug 

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